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Greensky Bio produces astaxanthin, citrus bioflavonoids, diosmin, red yeast rice, NMN, NR, PQQ, ergothioneine, and various other plant extracts and nutritional ingredients.

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home > FAQ > Artichoke Extract > Artichoke Extract with Cynarin: Liver Health and Digestive Support

Artichoke Extract with Cynarin: Liver Health and Digestive Support

2026-05-28

Artichoke Extract with Cynarin: Liver Health and Digestive Support

Published: 2026-05-23 | Updated: 2026-05-23 | By: Greensky Editorial Team

About Greensky

Hangzhou Greensky Biological Tech.Co.,Ltd (established 2004) is a professional manufacturer dedicated to natural plant extracts with over 20 years of experience. We are ISO22000, BRCGS, Ecocert Organic, and SGS-GMP certified, exporting to Europe, USA, South Korea, and Russia.

Q1: What is Cynarin and what are its health benefits?

This is an important question for anyone considering Artichoke Extract cynarin for their products or health needs.

At Greensky, with over 20 years of experience in natural plant extracts, we approach this topic with scientific rigor and practical expertise. Our R&D team, equipped with advanced laboratory facilities including GC, HPLC, and UV analysis capabilities, ensures all information is backed by thorough testing and research.

For specific technical details, specifications, or custom requirements related to Artichoke Extract cynarin, we recommend contacting our professional sales team. We provide comprehensive documentation including Certificates of Analysis (COA), Safety Data Sheets (SDS), and regulatory compliance documents for all our products.

Key Points:

Greensky is a GMP-certified manufacturer established in 2004
All products undergo rigorous quality testing
We export to Europe, USA, South Korea, and Russia
Custom formulations and technical support available

Q2: How is artichoke extract standardized for Cynarin content?

This is an important question for anyone considering artichoke extract cynarin for their products or health needs.

For specific technical details, specifications, or custom requirements related to artichoke extract cynarin, we recommend contacting our professional sales team. We provide comprehensive documentation including Certificates of Analysis (COA), Safety Data Sheets (SDS), and regulatory compliance documents for all our products.

Key Points:

Greensky is a GMP-certified manufacturer established in 2004
All products undergo rigorous quality testing
We export to Europe, USA, South Korea, and Russia
Custom formulations and technical support available

Q3: What are the traditional uses of artichoke extract?

This is an important question for anyone considering artichoke extract cynarin for their products or health needs.

Key Points:

Greensky is a GMP-certified manufacturer established in 2004
All products undergo rigorous quality testing
We export to Europe, USA, South Korea, and Russia
Custom formulations and technical support available

Q4: What clinical research supports artichoke extract benefits?

This is an important question for anyone considering artichoke extract cynarin for their products or health needs.

Key Points:

Greensky is a GMP-certified manufacturer established in 2004
All products undergo rigorous quality testing
We export to Europe, USA, South Korea, and Russia
Custom formulations and technical support available

Q5: What forms of artichoke extract does Greensky supply?

This is an important question for anyone considering artichoke extract cynarin for their products or health needs.

Key Points:

Greensky is a GMP-certified manufacturer established in 2004
All products undergo rigorous quality testing
We export to Europe, USA, South Korea, and Russia
Custom formulations and technical support available

Technical Specifications

Extraction Process:

Raw Material: Artichoke leaves (Cynara scolymus L.) - harvested at optimal maturity
Pre-treatment:

Washing and sorting
Drying at 40-50°C (preserves heat-sensitive compounds)
Grinding to 20-40 mesh

Extraction Methods:

Ethanol concentration: 40-60%
Temperature: 50-60°C
Time: 2-3 hours
Better extraction of flavonoids (luteolin, apigenin)
Temperature: 80-90°C
Time: 2-3 hours
Solid-liquid ratio: 1:8 - 1:10
Multiple extractions (2-3 cycles)
Best for water-soluble compounds (cynarin, chlorogenic acid)
Water Extraction (Traditional):
Ethanol-Water Extraction (Optimized):

Purification & Concentration:

Filtration (100-200 mesh)
Vacuum concentration (< 60°C)
Spray drying (inlet: 160-180°C, outlet: 80-85°C)
Standardization to cynarin/chlorogenic acid content

Key Parameters:

Cynarin content: 0.5-5% (standardized)
Chlorogenic acid: 5-25%
Total flavonoids: 10-30%
DER (Drug Extract Ratio): 4:1 - 10:1

Quality Testing Methods:

Cynarin Quantification (HPLC-UV):

Column: C18 (250mm × 4.6mm, 5μm)
Mobile phase: Methanol / 0.1% formic acid (gradient)
Detection wavelength: 327nm
Flow rate: 1.0 mL/min
Column temperature: 30°C
Retention time: ~12 minutes
Quantification: External standard with cynarin reference

Chlorogenic Acid (HPLC-UV):

Same conditions as cynarin
Detection: 327nm
Retention time: ~8 minutes

Total Flavonoids (UV-Vis):

Aluminum chloride colorimetric method
Detection: 420nm
Expressed as luteolin-7-glucoside equivalents

Heavy Metals: ICP-MS (Pb ≤ 2.0 ppm, As ≤ 1.0 ppm, Hg ≤ 0.1 ppm, Cd ≤ 0.5 ppm)
Pesticide Residues: GC-MS/LC-MS/MS (500+ compounds)
Microbiological: TP ≤ 10,000 CFU/g, Mold/Yeast ≤ 500 CFU/g, Pathogens negative
Aflatoxins: HPLC-FLD (B1, B2, G1, G2 < 10 ppb total)

Applications & Dosage:

Liver Health Supplements:

Liver support capsules: 300-600mg per serving (standardized to 5% cynarin)
Detoxification formulas: 500-1000mg daily
Combination with milk thistle, dandelion, turmeric

Digestive Health:

Bile production support: 300-500mg before meals
IBS relief formulas: 500mg 2-3 times daily
Combination with ginger, fennel, peppermint

Metabolic Support:

Cholesterol management: 500-1000mg daily
Blood sugar support: 300-500mg with meals
Weight management blends: With green tea, garcinia

Functional Foods:

Liver health beverages: 200-300mg per serving
Digestive teas: 1-2g dried extract per cup
Health tonics (traditional European formulations)

Clinical Evidence:

Liver function support: Multiple studies show improvement in liver enzyme levels (ALT, AST)
Digestive benefits: Traditional use for dyspepsia, bloating, and IBS symptoms
Lipid metabolism: Studies indicate modest cholesterol-lowering effects
Antioxidant activity: Strong free radical scavenging capacity

Safety Notes: