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Vitamin B12 5'-Deoxyadenosylcobalamin: Complete Guide to Benefits, Applications and Quality

2026-04-22

What is Vitamin B12 5'-Deoxyadenosylcobalamin?

5'-Deoxyadenosylcobalamin (also known as dibencozide) is one of the two naturally occurring, biologically active coenzyme forms of Vitamin B12 found in the human body. Unlike the synthetic cyanocobalamin form, 5'-deoxyadenosylcobalamin requires no conversion and can be utilized immediately by the body, making it the preferred choice for individuals with genetic variations (such as MTHFR mutations) that impair B12 metabolism.

Key Benefits

  • Active Coenzyme Form: The naturally occurring, bioactive form of B12 that the body can use immediately without requiring hepatic conversion.

  • Energy Production: Essential cofactor for methylmalonyl-CoA mutase, a key enzyme in the conversion of food into cellular energy (ATP).

  • Nervous System Support: Critical for maintaining the myelin sheath that protects nerve fibers and supports efficient nerve signal transmission.

  • Red Blood Cell Formation: Supports healthy red blood cell production and helps prevent megaloblastic anemia.

  • DNA Synthesis: Required for DNA replication and cell division, supporting healthy tissue growth and repair throughout the body.

Product Specifications

SpecificationDetails
Chemical Name5'-Deoxyadenosylcobalamin (Dibencozide)
CAS Number13870-90-1
Purity≥98.5% (HPLC)
GradeFood Grade
Test MethodHPLC
AppearanceDark red crystalline powder
SolubilitySparingly soluble in water
StorageStore in cool, dry place, away from light
Shelf Life24 months
Packaging1kg/drum or customized

Applications

  • Active B12 dietary supplements

  • Methylation support formulations

  • Energy and vitality products

  • Pharmaceutical formulations

Quality Standards

  • Manufactured in GMP-certified facility

  • Third-party lab tested for identity, potency, and purity

  • Free from heavy metals, pesticides, and microbial contamination

  • Compliant with USP, EP, and CP standards

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