Vitamin A Retinyl Acetate

Vitamin A Retinyl Acetate

Product Overview

Product Name: Vitamin A (Retinyl Acetate)  Potency: 500,000 IU/g (500,000 U/g)  Chemical Form: Retinyl Acetate  Appearance: Light Yellow to Yellow Powder/Crystals  CAS Number: 127-47-9  Molecular Formula: C₂₂H₃₂O₂

What is Vitamin A Retinyl Acetate?

Vitamin A retinyl acetate is a stable, esterified form of vitamin A (retinol). This fat-soluble vitamin is essential for vision, immune function, reproduction, and cellular communication. Our pharmaceutical-grade retinyl acetate provides 500,000 IU per gram, making it ideal for supplementation and fortification applications.

Manufacturing Process

Synthesis

• Process: Esterification of retinol with acetic anhydride

• Purification: Multiple crystallization steps

• Standardization: Dilution to specified potency

Purification

• Column chromatography

• Recrystallization from suitable solvents

• Removal of impurities and by-products

Standardization

• Potency adjustment to 500,000 IU/g

• May be diluted with carrier (gelatin, starch, or oil)

• Uniform distribution verified

Drying and Milling

• Vacuum drying at low temperature

• Milling to desired particle size

• Protected from light and oxygen throughout

Quality Testing Methods

Usage and Recommended Dosage

For Dietary Supplements

• Capsules/Softgels: 2,500-10,000 IU per serving (5-20mg extract)

• Daily Dosage (Adults): 2,300-3,000 IU RDA; upper limit 10,000 IU

• Timing: Best taken with meals containing fat for absorption

For Food Fortification

• Cereals: 1,500-3,000 IU per serving

• Dairy Products: 400-800 IU per serving

• Infant Formula: As per regulatory requirements

For Cosmetic Applications

• Anti-Aging Creams: 0.01-0.3% retinyl acetate

• Serums: 0.1-1% concentration

• Body Lotions: 0.05-0.5%

For Pharmaceutical

• Vitamin Deficiency Treatment: As directed by physician

• Dermatological Preparations: Topical formulations

• Ophthalmic Preparations: Eye health supplements

Storage Conditions

• Temperature: Store in cool place (2-8°C recommended; 15-25°C acceptable)

• Humidity: Relative humidity <50%

• Light: PROTECT FROM LIGHT (light-sensitive; amber containers required)

• Oxygen: Minimize exposure; nitrogen flushing recommended

• Packaging: Amber glass bottles or aluminum foil bags; double PE bags

• Shelf Life: 24 months from manufacturing date (when stored properly)

• After Opening: Use within 3 months; store in refrigerator; protect from light

Applications

Dietary Supplements

• Multivitamin formulations

• Vision support supplements

• Immune health products

• Prenatal vitamins

• Skin health supplements

Food Fortification

• Cereal fortification

• Dairy product enrichment

• Infant formula

• Margarine and spreads

• Beverage fortification

Cosmetics

• Anti-aging creams and serums

• Retinol-based skincare

• Acne treatment formulations

• Skin renewal products

Pharmaceutical

• Vitamin A deficiency treatment

• Dermatological preparations

• Ophthalmic supplements

• Oncology support (under medical supervision)

Safety Considerations

• Upper Limit: Do not exceed 10,000 IU daily without medical supervision

• Pregnancy: Limit to 3,000 IU (1,000 mcg RAE) during pregnancy

• Drug Interactions: May interact with retinoids, tetracyclines

• Toxicity: Chronic excessive intake can cause hypervitaminosis A

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