Study Highlights Effectiveness of Intermittent Fasting for Weight Loss

A recent study has revealed that adopting a 4:3 intermittent fasting regimen—fasting three days per week and eating freely the other four—may yield greater weight loss results compared to the traditional daily calorie-counting approach.1 Conducted by researchers, the study underscores the potential benefits of intermittent fasting, particularly when combined with physical activity, as participants found it easier to maintain long-term.

Study Details and Findings

This randomized controlled trial involved 165 individuals aged 18 to 60, although only 125 completed the study.1 Participants had body mass indexes (BMI) ranging from 17 to 46, with the threshold for overweight set between 25 and 29.9, and obesity defined as a BMI over 30.2 Subjects were randomly assigned to either a daily calorie restriction program or the 4:3 intermittent fasting plan for 12 months. The fasting group observed three non-consecutive fasting days, while eating unrestricted on the remaining days.1

Allison Rhodes, MD, an obesity medicine specialist from The Ohio State University Wexner Medical Center, noted the potential for overeating during non-fasting days. Nonetheless, the study results indicated that intermittent fasting led to "modestly greater weight loss," with the fasting group losing approximately six pounds more than the calorie restriction group.1

Factors Contributing to Intermittent Fasting's Effectiveness

One reason for the success of intermittent fasting could be the reduced cognitive and physical strain compared to daily calorie counting, which involves rigorous tracking and potential hunger. According to Rhodes, this method alleviates the daily burden of calorie counting, making it more manageable for participants.

Keerthana Kesavarapu, DO, an associate professor of medicine at Rutgers Health Robert Wood Johnson Medical School, affirmed that maintaining a continuous calorie deficit might be challenging. Despite a 26% dropout rate, Kesavarapu suggested that more participants adhered to the 4:3 fasting diet due to its simplicity.

Choosing the Right Weight Loss Approach

While intermittent fasting holds promise, individuals interested in losing weight should seek professional guidance. Rhodes emphasized the importance of tailoring strategies to individual needs, considering factors like nutritional access, daily habits, and food preparation methods.

Ultimately, whether intermittent fasting or daily caloric restriction, personalized plans designed by healthcare professionals can support sustainable and effective weight management.